| Date | Location | Result | |
| Nov 06, 2010 | Charlotte, NC | Johnson C. Smith 26, Livingstone College 13 | Box score |
| Oct 30, 2010 | Fayetteville, NC | Fayetteville State 64, Johnson C. Smith 6 | Box score |
| Oct 23, 2010 | Charlotte, NC | St. Augustine's 34, Johnson C. Smith 24 | Box score |
| Oct 16, 2010 | Richmond, VA | Virginia Union 44, Johnson C. Smith 21 | Box score |
| Oct 09, 2010 | Charlotte, NC | Shaw 45, Johnson C. Smith 7 | Box score |
| Oct 02, 2010 | Charlotte, NC | Winston Salem 49, Johnson C. Smith 3 | Box score |
| Sep 18, 2010 | Charlotte, NC | Brevard 25, JCSU 21 | Box score |
| Sep 11, 2010 | Charlotte, NC | JCSU 45, West Virginia Tech 21 | Box score |
| Sep 02, 2010 | Durham, NC | N.C. Central 59, JCSU 0 | Box score |
| Aug 28, 2010 | Elizabeth City,NC | Elizabeth City State 45, JCSU 27 | Box score |